Research & Projects

Based on deep research and clear theses for impact, we partner with outstanding researchers, policy entrepreneurs, and advocates who share our vision of making pandemics history within our lifetime. 

Our approach

Research-first

Our extensive analysis serves as the foundation for everything we do. Through internal studies, commissioned research, and external collaborations, we investigate action-guiding questions and scrutinize the assumptions behind our strategy.

Thesis-driven

We start from our strategic objectives and then find the right execution partners. We source these partnerships through our networks in government, industry, and civil society, evaluating them with our expert advisors. We also flexibly respond to exceptional opportunities outside our core goals, providing surge capacity for time-sensitive efforts.

Pragmatism in everything

We refuse to limit ourselves to the methods of traditional grantmaking and instead work with our partners to creatively pursue shared goals. Whether through commissioned research, grants, contracts, or collaborative projects, we find the most practical ways to establish strong partnerships around clear objectives. We support interventions spanning research to inform leading decision-makers, advocacy to shape national and international policy, high-level convenings, and talent development.

Balancing accountability and flexibility

We strive to keep ourselves and our partners accountable to an extraordinarily high standard for impact, without burying anyone in cumbersome reporting requirements. Our monitoring and evaluations prioritize thoughtfulness over performative rigor, answering the most important questions instead of being exhaustive.

Research & Projects

Johns Hopkins Center for Health Security
August 2025
Nucleic acid governance
$226,344
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Helena
July 2025
Biosecurity and AI; Nucleic acid governance
$75,000
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SecureBio
June 2025
Biosecurity and AI
$600,000
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Biosecurity Research Team
June 2025
Nucleic acid governance
$110,000
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Renaissance Philanthropy
May 2025
Biosecurity and AI; Nucleic acid governance
$25,000
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Independent Biosecurity Researcher
May 2025
Nucleic acid governance
$1,025
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Biosecurity Research Team
April 2025
Nucleic acid governance
$110,000
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Biosecurity Event at SynBioBeta
April 2025
Nucleic acid governance
$2,500
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Centre for Long-Term Resilience
February 2025
Biosecurity and AI
$400,000
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Pandemic Action Network
February 2025
Nucleic acid governance
$250,000
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Foreign Policy
February 2025
Building the ecosystem
$5,000
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Asia Centre for Health Security
January 2025
Nucleic acid governance
$75,000
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Asia Centre for Health Security
January 2025
Building the ecosystem
$750,000*
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Council on Strategic Risks
November 2024
Biosecurity and AI
$307,258
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Johns Hopkins Center for Health Security
November 2024
Building the ecosystem
$1,076,000*
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University of Maryland – Department of Computer Science
September 2024
Biosecurity and AI; 
Nucleic acid governance
$164,468
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Biosecurity research team
September 2024
Biosecurity and AI
$286,619
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Independent biosecurity researcher
August 2024
Nucleic acid governance
$75,000
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Epoch AI
August 2024
Biosecurity and AI
$80,000
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Pandemic Action Network
July 2024
Nucleic acid governance
$150,000
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Engineering Biology Research Consortium
June 2024
Nucleic acid governance
$330,000
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Open Molecular Software Foundation
June 2024
Biosecurity and AI
$50,000
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Independent public health researcher
July 2024
Building the ecosystem
$1,800
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*Funding provided by external partner at recommendation of Sentinel Bio